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SHA 68

简要描述:

SHA 68,CAS:24211-36-7

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SHA 68,CAS:24211-36-7

Biological Activity

Selective neuropeptide S receptor (NPSR) antagonist (IC50 values are 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively). Displays no activity against a range of 14 GPCRs, including vasopressin and oxytocin receptors.

Compound Libraries

SHA 68 is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt445.49
FormulaC26H24FN3O3
StorageStore at +4°C
Purity≥98% (HPLC)
CAS Number847553-89-3
PubChem ID11374217
InChI KeySFRQIPRTNYHJHP-UHFFFAOYSA-N
SmilesO=C(NCC4=CC=C(F)C=C4)N1CC2N(C(OC(C5=CC=CC=C5)2C3=CC=CC=C3)=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

 SolventMax Conc. mg/mLMax Conc. mM
Solubility
DMSO44.55100
ethanol44.55100

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